2015 was a busy year for the lab as we continue to study the mechanisms of protein homeostasis in mitochondria. We were delighted to receive five years of funding from the NIH to investigate how proteases in mitochondria recognize and destroy damaged and unnecessary proteins. Steven gave invited seminars at University of Nebraska, Lincoln and the Biophysical Society Annual Meeting. Two graduate students, Anthony Rampello (MCB) and Bojian Ding (BSB) successfully defended their thesis proposals in the Spring, and Anthony won a prize for best poster at the annual MCB/BSB graduate program retreat. The lab also welcomed Luke McGoldrick as a project aide to push our efforts in protein crystallization.